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Research3 days ago 4 min read

Pooled analysis: AOD-9604 shows no meaningful fat loss vs placebo

A six-trial meta-analysis pours cold water on a popular marketing claim.

by Editorial team

The analysis

Researchers pooled data from six placebo-controlled trials of AOD-9604, covering about 900 adults with obesity.

All trials were 12 weeks or longer.

What was found

Mean weight change versus placebo was less than 0.5 kg, with confidence intervals crossing zero.

No consistent effect was seen on body composition by DXA.

Why it matters

AOD-9604 is widely marketed as a fat-loss peptide.

This pooled analysis suggests those claims are not supported by controlled human data.