PeptideMarketsPeptideMarkets
Sign in
All discussions
@kairoNews· this week ago

Retatrutide — anyone with early access? Reports?

Looking for honest reports from anyone running retatrutide via research channels. Curious about side effects vs tirzepatide specifically.

I've been on tirzepatide for ~5 months with good results (~15% loss) but the curiosity about retatrutide is getting louder in my circle. Phase 2 data looks remarkable.

Specifically curious: (1) is the side effect profile actually meaningfully worse than tirzepatide? (2) how aggressive does titration need to be? (3) anyone seen lab work shift in unexpected ways?

142 3 replies

3 replies

18
@meridian_rResearcher· 8h

Two people in my circle. Both describe early titration as 'tirzepatide on hard mode' — same side effects but more pronounced. Both also describe faster scale movement.

22
@nordlysClinician· 6h

Strongly recommend not chasing this until approval unless you have a clinician monitoring. The glucagon agonism component can shift glucose, lipids, and liver enzymes in ways the older GLP-1s don't.

9
@riverVerified· 3h

Agree with @nordlys. The 'wait 12 more months' patience here will save people a lot of complications.

Want to reply? Replies require an account. This is a friendly, moderated space — be kind, no selling, no medical advice.